Dataset Information
Submitochondrial particles from bovine heart
Ontology highlight
ABSTRACT:
SUBMITTER: Atsuki Nakano
PROVIDER: EMPIAR-13484 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Structures of respiratory supercomplexes and ATP synthase oligomers in mammalian mitochondrial inner membrane.
Nature communications 20260317 1
Understanding the functional mechanisms of membrane protein complexes requires structural analysis within their native membrane environment. Here, we applied cryo-electron microscopy to determine the structures of F<sub>o</sub>F<sub>1</sub> ATP synthase and respiratory supercomplexes (SCs) on sub-mitochondrial particles (SMPs) isolated from bovine heart mitochondria. Most F<sub>o</sub>F<sub>1</sub> complexes were observed as dimers stabilized by the regulatory factor IF₁, and a tetrameric assemb ...[more]
