Endresen1997_SinoatrialActionPotential

ABSTRACT:

This a model from the article:
Chaos in weakly-coupled pacemaker cells.
Endresen LP. J Theor Biol 1997 Jan 7;184(1):41-50 9039399 ,
Abstract:
A model of the rabbit sinoatrial action potential is introduced, based on amodel by Morris & Lecar. One cell is described by two nonlinear first-orderordinary differential equations, with ten constant parameters. The model is muchsimpler than most other models in use, but can reproduce perfectlyexperimentally recorded action potentials. The dynamics of two coupled cells,with and without the presence of periodic acetylcholine pulses, shows examplesof bifurcations and strange attractors, mathematical phenomena characterizingchaotic motion. It remains to be clarified whether such dynamics is actuallyobserved, for example in the small irregular variations of the normal heartrate.

This model was taken from the CellML repository and automatically converted to SBML.
The original model was: Endresen LP. (1996) - version01
The original CellML model was created by:
Noble, Penny, J
[e-mail]
Oxford University
Department of Physiology, Anatomoy & Genetics

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ORGANISM(S): Oryctolagus cuniculus

SUBMITTER: Vijayalakshmi Chelliah 

PROVIDER: MODEL0912388235 | biostudies-other |

SECONDARY ACCESSION(S): 9039399

REPOSITORIES: biostudies-other