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Mol2013 - Leishmania macrophage signaling network


ABSTRACT:

Created by The MathWorks, Inc. SimBiology tool, Version 3.3

ORGANISM(S): Leishmania

SUBMITTER: Shailza Singh 

PROVIDER: MODEL1203220000 | biostudies-other |

SECONDARY ACCESSION(S): 24432155

REPOSITORIES: biostudies-other

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Publications

Signaling networks in Leishmania macrophages deciphered through integrated systems biology: a mathematical modeling approach.

Mol Milsee M   Patole Milind S MS   Singh Shailza S  

Systems and synthetic biology 20130704 4


Network of signaling proteins and functional interaction between the infected cell and the leishmanial parasite, though are not well understood, may be deciphered computationally by reconstructing the immune signaling network. As we all know signaling pathways are well-known abstractions that explain the mechanisms whereby cells respond to signals, collections of pathways form networks, and interactions between pathways in a network, known as cross-talk, enables further complex signaling behavio  ...[more]

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