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Büchel2013 - Dopaminergic Nerve Cell Model


ABSTRACT: N/A

SUBMITTER: Finja Büchel 

PROVIDER: MODEL1302200000 | biostudies-other |

SECONDARY ACCESSION(S): 24195591

REPOSITORIES: biostudies-other

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Publications

Parkinson's disease: dopaminergic nerve cell model is consistent with experimental finding of increased extracellular transport of α-synuclein.

Büchel Finja F   Saliger Sandra S   Dräger Andreas A   Hoffmann Stephanie S   Wrzodek Clemens C   Wrzodek Clemens C   Zell Andreas A   Kahle Philipp J PJ  

BMC neuroscience 20131106


<h4>Background</h4>Parkinson's disease is an age-related disease whose pathogenesis is not completely known. Animal models exist for investigating the disease but not all results can be easily transferred to humans. Therefore, mathematical or probabilistic models for the human disease are to be constructed in silico in order to predict specific processes within a cell, such as the dopamine metabolism and transport processes in a neuron.<h4>Results</h4>We present a Systems Biology Markup Language  ...[more]

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