Dataset Information
Mardinoglu2013 - Genome-scale metabolic model (HMR version 1.0) - generic human cell
Ontology highlight
ABSTRACT:
SUBMITTER: Adil Mardinoglu
PROVIDER: MODEL1402200000 | biostudies-other |
SECONDARY ACCESSION(S): 23511207
REPOSITORIES: biostudies-other
Publications
Integration of clinical data with a genome-scale metabolic model of the human adipocyte.
Molecular systems biology 20130101
We evaluated the presence/absence of proteins encoded by 14 077 genes in adipocytes obtained from different tissue samples using immunohistochemistry. By combining this with previously published adipocyte-specific proteome data, we identified proteins associated with 7340 genes in human adipocytes. This information was used to reconstruct a comprehensive and functional genome-scale metabolic model of adipocyte metabolism. The resulting metabolic model, iAdipocytes1809, enables mechanistic insigh ...[more]
