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Mazein2013 - Cholesterol biosynthesis pathway

ABSTRACT: N/A

SUBMITTER: Alexander Mazein

PROVIDER: MODEL1409170000 | biostudies-other |

SECONDARY ACCESSION(S): 23583456

REPOSITORIES: biostudies-other

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A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway.

Mazein Alexander A Watterson Steven S Hsieh Wei-Yuan WY Griffiths William J WJ Ghazal Peter P

Biochemical pharmacology 20130410 1

Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. A detailed, integrative single-view description of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking in the existing literature. Here we provide a systematic review of the existing literature and present a detailed pathway diagram that describes the cholesterol biosynthesis pathway (the mevalonate, the Kandutch-Russell and the Bloc ...[more]

PMID: 23583456

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