Dataset Information
Kerkhoven2016 - Genome-scale metabolic model of Yarrowia lipolytica
Ontology highlight
ABSTRACT:
SUBMITTER: Eduard Kerkhoven
PROVIDER: MODEL1508190002 | biostudies-other |
SECONDARY ACCESSION(S): 28725468
REPOSITORIES: biostudies-other
Publications
Regulation of amino-acid metabolism controls flux to lipid accumulation in <i>Yarrowia lipolytica</i>.
NPJ systems biology and applications 20160303
<i>Yarrowia lipolytica</i> is a promising microbial cell factory for the production of lipids to be used as fuels and chemicals, but there are few studies on regulation of its metabolism. Here we performed the first integrated data analysis of <i>Y. lipolytica</i> grown in carbon and nitrogen limited chemostat cultures. We first reconstructed a genome-scale metabolic model and used this for integrative analysis of multilevel omics data. Metabolite profiling and lipidomics was used to quantify th ...[more]