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Khanin1998 - Mathematical Model of Blood Coagulation Prothrombin Time Test


ABSTRACT: Blood coagulation model for prothrombin time test.

ORGANISM(S): Homo sapiens

SUBMITTER: Matthew Roberts 

PROVIDER: MODEL1806120001 | biostudies-other |

SECONDARY ACCESSION(S): 9645916

REPOSITORIES: biostudies-other

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Mathematical model for the blood coagulation prothrombin time test.

Khanin M A MA   Rakov D V DV   Kogan A E AE  

Thrombosis research 19980301 5


A mathematical model for the prothrombin time test is proposed. The time course of clotting factor activation during coagulation was calculated, and the sensitivity of the test to a decrease in the concentrations of coagulation proteins or their activities was studied. The model predicts that only severe coagulation disorders connected with a more than five-fold decrease in the concentrations or activities of the blood coagulation factors can be revealed by the test. ...[more]

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