Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Matthew Roberts
PROVIDER: MODEL1806120001 | biostudies-other |
SECONDARY ACCESSION(S): 9645916
REPOSITORIES: biostudies-other

Thrombosis research 19980301 5
A mathematical model for the prothrombin time test is proposed. The time course of clotting factor activation during coagulation was calculated, and the sensitivity of the test to a decrease in the concentrations of coagulation proteins or their activities was studied. The model predicts that only severe coagulation disorders connected with a more than five-fold decrease in the concentrations or activities of the blood coagulation factors can be revealed by the test. ...[more]