Dataset Information
Panteleev2010 - Blood Coagulation: Full Model
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Lucian Smith
PROVIDER: MODEL1808160002 | biostudies-other |
SECONDARY ACCESSION(S): 20441738
REPOSITORIES: biostudies-other
Publications
Task-oriented modular decomposition of biological networks: trigger mechanism in blood coagulation.
Biophysical journal 20100501 9
Analysis of complex time-dependent biological networks is an important challenge in the current postgenomic era. We propose a middle-out approach for decomposition and analysis of complex time-dependent biological networks based on: 1), creation of a detailed mechanism-driven mathematical model of the network; 2), network response decomposition into several physiologically relevant subtasks; and 3), subsequent decomposition of the model, with the help of task-oriented necessity and sensitivity a ...[more]
