Dataset Information
Zhang2018 - Cell cycle commitment in hypoxia
Ontology highlight
ABSTRACT: Does not reproduce publication figure 3
SUBMITTER: Ashley Xavier
PROVIDER: MODEL1812060002 | biostudies-other |
SECONDARY ACCESSION(S): 29606139
REPOSITORIES: biostudies-other
Publications
Mathematical modelling of interacting mechanisms for hypoxia mediated cell cycle commitment for mesenchymal stromal cells.
BMC systems biology 20180402 1
<h4>Background</h4>Existing experimental data have shown hypoxia to be an important factor affecting the proliferation of mesenchymal stromal cells (MSCs), but the contrasting observations made at various hypoxic levels raise the questions of whether hypoxia accelerates proliferation, and how. On the other hand, in order to meet the increasing demand of MSCs, an optimised bioreactor control strategy is needed to enhance in vitro production.<h4>Results</h4>A comprehensive, single-cell mathematica ...[more]
