Dataset Information
Hansen2019 - Seven species reduced model of blood coagulation
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Krishna Kumar Tiwari
PROVIDER: MODEL1907180003 | biostudies-other |
SECONDARY ACCESSION(S): 31161687
REPOSITORIES: biostudies-other
Publications
Automated reduction of blood coagulation models.
International journal for numerical methods in biomedical engineering 20190829 10
Mathematical modeling of thrombosis typically involves modeling the coagulation cascade. Models of coagulation generally involve the reaction kinetics for dozens of proteins. The resulting system of equations is difficult to parameterize, and its numerical solution is challenging when coupled to blood flow or other physics important to clotting. Prior research suggests that essential aspects of coagulation may be reproduced by simpler models. This evidence motivates a systematic approach to mode ...[more]
