Dataset Information
DePillis2005 - A validated mathematical model of cell-mediated immune response to tumor growth
Ontology highlight
ABSTRACT: This model describes interactions between a tumour and the immune system, with specific emphasis on the role of natural killer and CD8-positive T cells in tumor surveillance. The model features descriptions of tumor-immune cell interactions using ODEs, which allow the prediction of tumor growth, response, and interaction rates.
ORGANISM(S): Mus musculus
SUBMITTER: Johannes Meyer
PROVIDER: MODEL1907260001 | biostudies-other |
SECONDARY ACCESSION(S): 16140967
REPOSITORIES: biostudies-other
Publications
A validated mathematical model of cell-mediated immune response to tumor growth.
Cancer research 20050901 17
Mathematical models of tumor-immune interactions provide an analytic framework in which to address specific questions about tumor-immune dynamics. We present a new mathematical model that describes tumor-immune interactions, focusing on the role of natural killer (NK) and CD8+ T cells in tumor surveillance, with the goal of understanding the dynamics of immune-mediated tumor rejection. The model describes tumor-immune cell interactions using a system of differential equations. The functions desc ...[more]