Dataset Information
Lopez2014 - A Validated Mathematical Model of Tumor Growth Including Tumor-Host Interaction and Cell-Mediated Immune Response
Ontology highlight
ABSTRACT: This is a dynamical model of cancer growth that includes three interacting cell populations of tumor cells, healthy host cells and immune effector cells. The tumor-immune and the tumor-host interactions are characterized to reproduce experimental results.
ORGANISM(S): Mus musculus
SUBMITTER: Lucian Smith
PROVIDER: MODEL1908090001 | biostudies-other |
SECONDARY ACCESSION(S): 25348062
REPOSITORIES: biostudies-other
Publications
A validated mathematical model of cell-mediated immune response to tumor growth.
Cancer research 20050901 17
Mathematical models of tumor-immune interactions provide an analytic framework in which to address specific questions about tumor-immune dynamics. We present a new mathematical model that describes tumor-immune interactions, focusing on the role of natural killer (NK) and CD8+ T cells in tumor surveillance, with the goal of understanding the dynamics of immune-mediated tumor rejection. The model describes tumor-immune cell interactions using a system of differential equations. The functions desc ...[more]
