Dataset Information
Rangel-Reyes2017 - Dendritic Immunotherapy Improvement for an Optimal Control Murine Model
Ontology highlight
ABSTRACT: This is a mathematical model provides a platform for investigating the efficacy of dendritic cell vaccines during cancer treatment while accounting for obstacles such as immunosuppression and poor transference to the lymphatic system.
ORGANISM(S): Mus musculus
SUBMITTER: Johannes Meyer
PROVIDER: MODEL1909160002 | biostudies-other |
SECONDARY ACCESSION(S): 28912828
REPOSITORIES: biostudies-other
Publications
Improving T-cell immunotherapy for melanoma through a mathematically motivated strategy: efficacy in numbers?
Journal of immunotherapy (Hagerstown, Md. : 1997) 20120201 2
T-cell mediated immunotherapy for malignant diseases has become an effective treatment option, especially in malignant melanoma. Recent advances have enabled the transfer of high T-cell numbers with high functionality. However, with more T cells becoming technically available for transfer, questions about dose, treatment schedule, and safety become most relevant. Mathematical oncology can simulate tumor characteristics in silico and predict the tumor response to novel therapeutics. Using similar ...[more]
