Dataset Information
Fribourg2014 - Model of influenza A virus infection dynamics of viral antagonism and innate immune response.
Ontology highlight
ABSTRACT: This is an ordinary differential equation mathematical model investigating the early responses of human monocyte-derived dendritic cells to infection by two H1N1 influenza A viruses of different clinical outcomes: pandemic A/California/4/2009 and seasonal A/New Caledonia/20/1999.
ORGANISM(S): Homo sapiens
SUBMITTER: Lucian Smith
PROVIDER: MODEL1912120001 | biostudies-other |
SECONDARY ACCESSION(S): 24594370
REPOSITORIES: biostudies-other
Publications
Model of influenza A virus infection: dynamics of viral antagonism and innate immune response.
Journal of theoretical biology 20140302
Viral antagonism of host responses is an essential component of virus pathogenicity. The study of the interplay between immune response and viral antagonism is challenging due to the involvement of many processes acting at multiple time scales. Here we develop an ordinary differential equation model to investigate the early, experimentally measured, responses of human monocyte-derived dendritic cells to infection by two H1N1 influenza A viruses of different clinical outcomes: pandemic A/Californ ...[more]