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Schokker2013 - A mathematical model representing cellular immune development and response to Salmonella of chicken intestinal tissue


ABSTRACT:

This is a dynamic mathematical model describing the development of the cellular branch of the intestinal immune system of poultry during the first 42 days of life, and of its response towards an oral infection with Salmonella enterica serovar Enteritidis.

ORGANISM(S): Gallus gallus

SUBMITTER: Lucian Smith 

PROVIDER: MODEL1912160004 | biostudies-other |

SECONDARY ACCESSION(S): 23603730

REPOSITORIES: biostudies-other

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Publications

A mathematical model representing cellular immune development and response to Salmonella of chicken intestinal tissue.

Schokker D D   Bannink A A   Smits M A MA   Rebel J M J JM  

Journal of theoretical biology 20130418


The aim of this study was to create a dynamic mathematical model of the development of the cellular branch of the intestinal immune system of poultry during the first 42 days of life and of its response towards an oral infection with Salmonella enterica serovar Enteritidis. The system elements were grouped in five important classes consisting of intra- and extracellular S. Enteritidis bacteria, macrophages, CD4+, and CD8+ cells. Twelve model variables were described by ordinary differential equa  ...[more]

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