Dataset Information
Phillips2013 - physiologically based modeling explaining Mammalian rest/activity patterns
Ontology highlight
ABSTRACT:
ORGANISM(S): Mammalia
SUBMITTER: Lucian Smith
PROVIDER: MODEL2003080001 | biostudies-other |
SECONDARY ACCESSION(S): 24039566
REPOSITORIES: biostudies-other
Publications
Mammalian rest/activity patterns explained by physiologically based modeling.
PLoS computational biology 20130905 9
Circadian rhythms are fundamental to life. In mammals, these rhythms are generated by pacemaker neurons in the suprachiasmatic nucleus (SCN) of the hypothalamus. The SCN is remarkably consistent in structure and function between species, yet mammalian rest/activity patterns are extremely diverse, including diurnal, nocturnal, and crepuscular behaviors. Two mechanisms have been proposed to account for this diversity: (i) modulation of SCN output by downstream nuclei, and (ii) direct effects of li ...[more]
