Dataset Information
Muenzner2019 - Yeast Cell cycle control network
Ontology highlight
ABSTRACT:
SUBMITTER: Ulrike Muenzner
PROVIDER: MODEL2007020001 | biostudies-other |
SECONDARY ACCESSION(S): 30899000
REPOSITORIES: biostudies-other
Publications
A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae.
Nature communications 20190321 1
Understanding how cellular functions emerge from the underlying molecular mechanisms is a key challenge in biology. This will require computational models, whose predictive power is expected to increase with coverage and precision of formulation. Genome-scale models revolutionised the metabolic field and made the first whole-cell model possible. However, the lack of genome-scale models of signalling networks blocks the development of eukaryotic whole-cell models. Here, we present a comprehensive ...[more]