Dataset Information
Sharma2022 - Temperature-dependent NAD biosynthesis model
Ontology highlight
ABSTRACT: A computational mathematical model of NAD biosynthesis via PncA and Nampt pathway in thermophiles. It includes the temperature dependence of the reaction rates.
SUBMITTER: Suraj Sharma
PROVIDER: MODEL2103290001 | biostudies-other |
SECONDARY ACCESSION(S): 10.3390/metabo12070569
REPOSITORIES: biostudies-other
Publications
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms.
The Journal of biological chemistry 20050823 43
Nicotinamide mononucleotide adenylyltransferase (NMNAT) is the central enzyme of the NAD biosynthetic pathway. Three human NMNAT isoforms have recently been identified, but isoform-specific functions are presently unknown, although a tissue-specific role has been suggested. Analyses of the subcellular localization confirmed NMNAT1 to be a nuclear protein, whereas NMNAT2 and -3 were localized to the Golgi complex and the mitochondria, respectively. This differential subcellular localization point ...[more]
