Ontology highlight
ABSTRACT:
SUBMITTER: feiran
PROVIDER: MODEL2109130002 | biostudies-other |
SECONDARY ACCESSION(S): 10.15252/msb.202110427
REPOSITORIES: biostudies-other

Molecular cell 20060701 2
Metabolic enzymes rarely regulate informational processes like gene expression. Yeast acetyl-CoA synthetases (Acs1p and 2p) are exceptional, as they are important not only for carbon metabolism but also are shown here to supply the acetyl-CoA for histone acetylation by histone acetyltransferases (HATs). acs2-Ts mutants exhibit global histone deacetylation, transcriptional defects, and synthetic growth defects with HAT mutants at high temperatures. In glycerol with ethanol, Acs1p is an alternate ...[more]