Unknown

Dataset Information

0

Lu2021-Genome scale metabolic models for yeast species of clade Phaffomycetaceae


ABSTRACT: This is genome-scale metabolic model of Cyberlindnera americana as the representative yeast species for the clade Phaffomycetaceae. This model was generated through homology search using a fungal pan-GEM largely based on Yeast8 for Saccharomyces cerevisiae, in addition to manual curation. This model has been produced by the Yeast-Species-GEMs project from Sysbio (www.sysbio.se). This is model version 1.0.0 accompanying the publication (DOI: 10.15252/msb.202110427), currently hosted on BioModels Database and identified by MODEL2109130008. Further curations of this model will be tracked in the GitHub repository: https://github.com/SysBioChalmers/Yeast-Species-GEMs Models for species of the same clade includes: Cyberlindnera fabianii; Cyberlindnera jadinii; Wickerhamomyces anomalus; Wickerhamomyces ciferrii; Starmera quercuum; Candida stellimalicola; Candida freyschussii; Cyberlindnera mrakii; Cyberlindnera misumaiensis; Candida montana; Barnettozyma californica; Barnettozyma hawaiiensis; Barnettozyma populi; Barnettozyma pratensis; Barnettozyma salicaria; Candida ponderosae; Wickerhamomyces hampshirensis; Wickerhamomyces bovis; Wickerhamomyces alni; Wickerhamomyces sp.; Cyberlindnera petersonii; Wickerhamomyces canadensis; Starmera amethionina; Phaffomyces opuntiae; Phaffomyces antillensis; Phaffomyces thermotolerans; Candida orba; Cyberlindnera saturnus; Cyberlindnera suaveolens; Cyberlindnera xylosilytica; Candida mycetangii; Candida vartiovaarae; Cyberlindnera maclurae; Cyberlindnera americana. These models are available in the zip file. To cite BioModels, please use: V Chelliah et al; BioModels: ten-year anniversary. Nucleic Acids Res 2015; 43 (D1): D542-D548. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to MIT License for more information.

SUBMITTER: feiran 

PROVIDER: MODEL2109130008 | biostudies-other |

SECONDARY ACCESSION(S): 10.15252/msb.202110427

REPOSITORIES: biostudies-other

altmetric image

Publications

Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription.

Takahashi Hidekazu H   McCaffery J Michael JM   Irizarry Rafael A RA   Boeke Jef D JD  

Molecular cell 20060701 2


Metabolic enzymes rarely regulate informational processes like gene expression. Yeast acetyl-CoA synthetases (Acs1p and 2p) are exceptional, as they are important not only for carbon metabolism but also are shown here to supply the acetyl-CoA for histone acetylation by histone acetyltransferases (HATs). acs2-Ts mutants exhibit global histone deacetylation, transcriptional defects, and synthetic growth defects with HAT mutants at high temperatures. In glycerol with ethanol, Acs1p is an alternate  ...[more]

Publication: 1/363

Similar Datasets

| MODEL2109240002 | biostudies-other
| MODEL2109130013 | biostudies-other
| MODEL2109130011 | biostudies-other
| MODEL2109130010 | biostudies-other
| MODEL2109130009 | biostudies-other
| MODEL2109130007 | biostudies-other
| MODEL2109130006 | biostudies-other
| MODEL2109130002 | biostudies-other
| MODEL2109130014 | biostudies-other
| MODEL2109130005 | biostudies-other