Feist2014 - Geobacter metallireducens GS-15 metabolism

ABSTRACT: Geobacter species are of great interest for environmental and biotechnology applications as they can carry out direct electron transfer to insoluble metals or other microorganisms and have the ability to assimilate inorganic carbon. Here, we report on the capability and key enabling metabolic machinery of Geobacter metallireducens GS-15 to carry out CO2 fixation and direct electron transfer to iron. An updated metabolic reconstruction was generated, growth screens on targeted conditions of interest were performed, and constraint-based analysis was utilized to characterize and evaluate critical pathways and reactions in G. metallireducens. The novel capability of G. metallireducens to grow autotrophically with formate and Fe(III) was predicted and subsequently validated in vivo. Additionall

ORGANISM(S): Geobacter metallireducens

SUBMITTER: Tung Nguyen 

PROVIDER: MODEL2204190002 | biostudies-other |

SECONDARY ACCESSION(S): 24762737

REPOSITORIES: biostudies-other