Dataset Information
Trares2022 - Non-canonical NF-kB pathway, Petri net
Ontology highlight
ABSTRACT:
SUBMITTER: Ann-Kathrin Otto
PROVIDER: MODEL2207210002 | biostudies-other |
SECONDARY ACCESSION(S): 34688841
REPOSITORIES: biostudies-other
Publications
The non-canonical NF-κB pathway in immunity and inflammation.
Nature reviews. Immunology 20170605 9
The nuclear factor-κB (NF-κB) family of transcription factors is activated by canonical and non-canonical signalling pathways, which differ in both signalling components and biological functions. Recent studies have revealed important roles for the non-canonical NF-κB pathway in regulating different aspects of immune functions. Defects in non-canonical NF-κB signalling are associated with severe immune deficiencies, whereas dysregulated activation of this pathway contributes to the pathogenesis ...[more]
