Dataset Information
Koduru2022 - Lactobacillus salivarius ATCC 11741
Ontology highlight
ABSTRACT:
ORGANISM(S): Ligilactobacillus salivarius DSM 20555 = ATCC 11741
SUBMITTER: Tung Nguyen
PROVIDER: MODEL2210190008 | biostudies-other |
SECONDARY ACCESSION(S): 36476869
REPOSITORIES: biostudies-other
Publications
Systematic evaluation of genome-wide metabolic landscapes in lactic acid bacteria reveals diet- and strain-specific probiotic idiosyncrasies.
Cell reports 20221201 10
Lactic acid bacteria (LAB) are well known to elicit health benefits in humans, but their functional metabolic landscapes remain unexplored. Here, we analyze differences in growth, intestinal persistence, and postbiotic biosynthesis of six representative LAB and their interactions with 15 gut bacteria under 11 dietary regimes by combining multi-omics and in silico modeling. We confirmed predictions on short-term persistence of LAB and their interactions with commensals using cecal microbiome abun ...[more]