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Koduru2022 - Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293


ABSTRACT: GEM reconstruction for Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

ORGANISM(S): Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y)

SUBMITTER: Tung Nguyen 

PROVIDER: MODEL2210190012 | biostudies-other |

SECONDARY ACCESSION(S): 36476869

REPOSITORIES: biostudies-other

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Publications

Systematic evaluation of genome-wide metabolic landscapes in lactic acid bacteria reveals diet- and strain-specific probiotic idiosyncrasies.

Koduru Lokanand L   Lakshmanan Meiyappan M   Lee Yi Qing YQ   Ho Pooi-Leng PL   Lim Pei-Yu PY   Ler Wei Xuan WX   Ng Say Kong SK   Kim Dongseok D   Park Doo-Sang DS   Banu Mazlina M   Ow Dave Siak Wei DSW   Lee Dong-Yup DY  

Cell reports 20221201 10


Lactic acid bacteria (LAB) are well known to elicit health benefits in humans, but their functional metabolic landscapes remain unexplored. Here, we analyze differences in growth, intestinal persistence, and postbiotic biosynthesis of six representative LAB and their interactions with 15 gut bacteria under 11 dietary regimes by combining multi-omics and in silico modeling. We confirmed predictions on short-term persistence of LAB and their interactions with commensals using cecal microbiome abun  ...[more]

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