Dataset Information
Amstein2017 - TNFR1-mediated Nf-κB signaling, Petri Net
Ontology highlight
ABSTRACT:
SUBMITTER: Ann-Kathrin Otto
PROVIDER: MODEL2312010001 | biostudies-other |
SECONDARY ACCESSION(S): 28754124
REPOSITORIES: biostudies-other
Publications
Manatee invariants reveal functional pathways in signaling networks.
BMC systems biology 20170728 1
<h4>Background</h4>Signal transduction pathways are important cellular processes to maintain the cell's integrity. Their imbalance can cause severe pathologies. As signal transduction pathways feature complex regulations, they form intertwined networks. Mathematical models aim to capture their regulatory logic and allow an unbiased analysis of robustness and vulnerability of the signaling network. Pathway detection is yet a challenge for the analysis of signaling networks in the field of systems ...[more]
