Zhou2024 - Post Infarction Myocyte Electromechanics

ABSTRACT: A human ventricular electromechanical modelling and simulation framework is constructed and validated with rich experimental and clinical datasets. Abnormalities caused by scar and border zone ionic remodeling are introduced in varying degrees as reported in experimental data obtained in acute and chronic infarction. Simulations enabled reproducing and explaining clinical phenotypes post-MI, from ionic remodelling to ECGs and pressure-volume loops.

SUBMITTER: XIN ZHOU 

PROVIDER: MODEL2402290004 | biostudies-other |

SECONDARY ACCESSION(S): 10.7554/eLife.93002.2

REPOSITORIES: biostudies-other