Project description:To study the changes and differences in gene expression levels during biofilm formation of two Pseudomonas aeruginosa sublines.

2025-06-16 | GSE299861 | GEO

Tobramycin Treatment of Pseudomonas aeruginosa

Project description:This SuperSeries is composed of the SubSeries listed below.

2008-06-10 | GSE10030 | GEO

Zinc acquisition in Pseudomonas aeruginosa

Project description:This study addresses the impact of zinc limitation on the opportunistic human pathogen, Pseudomonas aeruginosa. Zinc limitation was assessed in the P. aeruginosa PAO1 strain using an isogenic deletion mutant lacking the periplasmic, zinc solute-binding protein, znuA (PA5498). ZnuA delivers bound zinc to its cognate ABC transporter, ZnuBC, for import into the cytoplasm. Our transcriptional analyses revealed P. aeruginosa to possess a multitude of zinc acquisition mechanisms, each of which were highly up-regulated in the zinc-deficient znuA mutant strain. P. aeruginosa also utilized zinc-independent paralogues of zinc-dependent genes to maintain cellular function under zinc limitation. Together, these data reveal the complex transcriptional response and versatility of P. aeruginosa to zinc depletion.

2017-01-01 | GSE60177 | GEO

Replication transcriptome of Pseudomonas aeruginosa

Project description:Transcriptiomes of non-replicating, replicating and pre-divisonal P. aeruginosa PA14 FACS subpopulations during replication-coupled growth in LB medium.

2022-11-07 | GSE217100 | GEO

Dkstatin-treated Pseudomonas aeruginosa trascriptome

Project description:To better understand the effects of Dkstatin treatment, we compared transcriptome landscapes of PAO1 grown without or with either Dkstatin. A global view of the entire transcriptome uncovered the substantial differences between cells treated with Dkstatin-1 or Dkstatin-2.

2020-12-16 | GSE163248 | GEO

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