Ontology highlight
ABSTRACT: The model reproduces the temporal evolution of Glycogen phosphorylase for a vale of Vm5=30 as depicted in Fig 1a of the paper. The model makes use of calcium oscillations from the Borghans model to stimulate the activation of glycogen phosphorylase. Hence, this is a simple extension of the Borghans model. The model was succesfully tested on MathSBML and Jarnac. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
ORGANISM(S): cellular organisms
SUBMITTER: Lucian Smith
PROVIDER: MODEL4589754842 | biostudies-other |
SECONDARY ACCESSION(S): 14556891
REPOSITORIES: biostudies-other

Bulletin of mathematical biology 19990501 3
We investigate the various types of complex Ca2+ oscillations which can arise in a model based on the mechanism of Ca2+-induced Ca2+ release (CICR), that takes into account the Ca2+-stimulated degradation of inositol 1,4,5-trisphosphate (InsP3) by a 3-kinase. This model was previously proposed in the course of an investigation of plausible mechanisms capable of generating complex Ca2+ oscillations. Besides simple periodic behavior, this model for cytosolic Ca2+ oscillations in nonexcitable cells ...[more]