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Feist2006_methanogenesis_OptiPyruvate


ABSTRACT:

This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team.
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.

In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not..

To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

ORGANISM(S): Methanosarcina barkeri

SUBMITTER: Molecular Systems Biology 

PROVIDER: MODEL5662425708 | biostudies-other |

SECONDARY ACCESSION(S): 16738551

REPOSITORIES: biostudies-other

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Publications

Modeling methanogenesis with a genome-scale metabolic reconstruction of Methanosarcina barkeri.

Feist Adam M AM   Scholten Johannes C M JC   Palsson Bernhard Ø BØ   Brockman Fred J FJ   Ideker Trey T  

Molecular systems biology 20060131


We present a genome-scale metabolic model for the archaeal methanogen Methanosarcina barkeri. We characterize the metabolic network and compare it to reconstructions from the prokaryotic, eukaryotic and archaeal domains. Using the model in conjunction with constraint-based methods, we simulate the metabolic fluxes and resulting phenotypes induced by different environmental and genetic conditions. This represents the first large-scale simulation of either a methanogen or an archaeal species. Mode  ...[more]

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