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Mayya2005_STATmodule


ABSTRACT:

The model reproduces Fig 2B of the paper. Model successfully reproduced using MathSBML.


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To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

ORGANISM(S): cellular organisms

SUBMITTER: Lucian Smith 

PROVIDER: MODEL6095659304 | biostudies-other |

SECONDARY ACCESSION(S): 17091582

REPOSITORIES: biostudies-other

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Publications

The JAK-STAT signaling network in the human B-cell: an extreme signaling pathway analysis.

Papin Jason A JA   Palsson Bernhard O BO  

Biophysical journal 20040701 1


Large-scale models of signaling networks are beginning to be reconstructed and corresponding analysis frameworks are being developed. Herein, a reconstruction of the JAK-STAT signaling system in the human B-cell is described and a scalable framework for its network analysis is presented. This approach is called extreme signaling pathway analysis and involves the description of network properties with systemically independent basis vectors called extreme pathways. From the extreme signaling pathw  ...[more]

Publication: 1/3

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