Dataset Information
Leloup1999_CircClock
Ontology highlight
ABSTRACT: This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2009 The BioModels Team.
For more information see the terms of use.
To cite BioModels Database, please use Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Lucian Smith
PROVIDER: MODEL6617834203 | biostudies-other |
SECONDARY ACCESSION(S): 10366496
REPOSITORIES: biostudies-other
Publications
Chaos and birhythmicity in a model for circadian oscillations of the PER and TIM proteins in drosophila
Journal of theoretical biology 19990601 3
In Drosophila, circadian oscillations in the levels of two proteins, PER and TIM, result from the negative feedback exerted by a PER-TIM complex on the expression of the per and tim genes which code for these two proteins. On the basis of these experimental observations, we have recently proposed a theoretical model for circadian oscillations of the PER and TIM proteins in Drosophila. Here we show that for constant environmental conditions this model is capable of generating autonomous chaotic o ...[more]