Dataset Information
Sriram2007_CellCycle
Ontology highlight
ABSTRACT: The model reproduces the time profile of species depicted in Figure 12a and 12 b. The authors communicated to the curator that there is a typo in the paper, the values of kd1 and kd2 are reversed. Model successfully reproduced using MathSBML.
ORGANISM(S): Opisthokonta
SUBMITTER: Lucian Smith
PROVIDER: MODEL8610478473 | biostudies-other |
SECONDARY ACCESSION(S): 18203579
REPOSITORIES: biostudies-other
Publications
A minimal mathematical model combining several regulatory cycles from the budding yeast cell cycle.
IET systems biology 20071101 6
A novel topology of regulatory networks abstracted from the budding yeast cell cycle is studied by constructing a simple nonlinear model. A ternary positive feedback loop with only positive regulations is constructed with elements that activates the subsequent element in a clockwise fashion. A ternary negative feedback loop with only negative regulations is constructed with the elements that inhibit the subsequent element in an anticlockwise fashion. Positive feedback loop exhibits bistability, ...[more]