Genes related to Lysosomal storage disorders and Schizophrenia.

ABSTRACT: Recent data described that patients with lysosomal storage disorders (LSDs) may have clinical schizophrenia (SCZ) features. Four rare deleterious variants among LSDs genes causing mucopolysaccharidosis type I (IDUA (rs532731688, rs74385837) and type III (HGSNAT (rs766835582)) and sphingolipidosis (meta-chromatic leukodystrophy (ARSA (rs201251634)) were identified in five patients from the group of early-onset SCZ patients but not in the controls.

ORGANISM(S): Homo sapiens (human)

SUBMITTER:  

PROVIDER: S-BSST1274 | biostudies-other |

REPOSITORIES: biostudies-other