Making Safety Decisions for a Sunscreen Active Ingredient Using Next-Generation Risk Assessment: Benzophenone-4 Case Study

ABSTRACT: A dose response comparison of biomarker responses using the cell stress panel developed in the paper from Hatherell et al 2020, following treatment with the chemical compound Benzophenone-4 as part of case study to explore the application of Next Generation Risk Assessment approaches for a sunscreen active ingredient. Biomarker changes compared to baseline vehicle controls were used to estimate the POD - minimum effect concentration when a biological perturbation could be identified as part of a larger comparison of within an NGRA toolbox

ORGANISM(S): Homo sapiens (human)

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PROVIDER: S-BSST2023 | biostudies-other |

REPOSITORIES: biostudies-other