Clinical Significance of Serum IL-15 and IL-17 in Relation to Rheumatoid Arthritis' Severity and Activity

ABSTRACT: In this study, we measured serum IL-15 and IL-17 levels in a cohort of patients with rheumatoid arthritis (RA) in order to assess their relevance with the disease’s activity and severity, as well as delineating any potential correlation with various clinical and laboratory parameters routinely used to evaluate RA disease activity and severity. Peripheral blood samples were collected from all recruits and used for the estimation of serum IL-15, IL-17, anti-cyclic citrullinated peptide antibodies (anti-CCP), rheumatoid factor (RF) and C-reactive protein (CRP) as well as erythrocyte sedimentation rate (ESR). RA activity and severity were also determined using disease activity score 28 (DAS28) as well as tender joint count (TJC) and swollen joint count (SJC) respectively. RA patients showed si

ORGANISM(S): Homo sapiens (human)

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PROVIDER: S-BSST823 | biostudies-other |

REPOSITORIES: biostudies-other