Project description:Hepatocellular carcinoma samples were obtained after patients provided written informed consent and with the approval of the institutional research ethics board at the Liver Cancer Institute of Zhongshan Hospital, Fudan University (Shanghai, China). Fresh tumor tissues were implanted in NOD/SCID mice. Tumor lines were successfully maintained through multiple rounds of serial transplantation. We used microarrays to evaluate the expression similarity between patient tumor and patient-derived xenograft (PDX).

2016-12-01 | GSE90563 | GEO

SNP data from hepatocellular carcinoma PDX

Project description:Hepatocellular carcinoma samples were obtained after patients provided written informed consent and with the approval of the institutional research ethics board at the Liver Cancer Institute of Zhongshan Hospital, Fudan University (Shanghai, China). Fresh tumor tissues were implanted in NOD/SCID mice. Tumor lines were successfully maintained through multiple rounds of serial transplantation. We used microarrays to evaluate the genotype similarity between patient tumor and patient-derived xenograft (PDX).

2016-12-01 | GSE90651 | GEO

Resistance to Antiangiogenic Therapies by Metabolic Symbiosis in Renal Cell Carcinoma PDX Models and Patients.

Project description: Not available

| S-EPMC4870515 | biostudies-literature

Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines.

Project description: Not available

| S-EPMC8643474 | biostudies-literature

The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development.

Project description: Not available

| S-EPMC7501166 | biostudies-literature

Streptococcus pneumoniae R6 strain:R6

Project description:Avirulent isolate