Project description:The Trophoblast cell surface antigen 2 (TROP2) is a transmembrane glycoprotein encoded by the Tumor associated calcium signal transducer 2 (TACSTD2) gene. TROP2 is upregulated in many human malignancies including colorectal cancer, and its overexpression correlates with tumor progression, invasiveness, and poor survival. Functional studies revealed that TROP2 may have a role as both an oncogene and a tumor suppressor. To identify TROP2 function in human cancer cells, we performed gene expression profiling of TROP2+ and TROP2- cells isolated from human colon tumors. Due to the sensitive nature of the data, raw data files have not been uploaded.

2022-12-31 | E-MTAB-11466 | biostudies-arrayexpress

SUNRISE-CRC: a randomized phase II study of high-dose intermittent sunitinib versus trifluridine/tipiracil in metastatic colorectal carcinoma.

Project description: Not available

| S-EPMC12573252 | biostudies-literature

ctDNA to Guide Adjuvant Therapy in Localized Colorectal Cancer (CRC).

Project description: Not available

| S-EPMC8226638 | biostudies-literature

Birth Cohort Colorectal Cancer (CRC): Implications for Research and Practice.

Project description: Not available

| S-EPMC11304405 | biostudies-literature

Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models.

Project description: Not available