Kidney transplantation

ABSTRACT: In this study, we examined transcriptional profiles from 3 different microarray platforms, across 103 peripheral blood samples with and without acute rejection, to find a critical gene-set for the diagnosis of acute renal rejection that matched biopsy diagnosis, irrespective of patient demographics, clinical confounders, concomitant infection, immunosuppression usage or sample processing methods. We hypothesized that changes in peripheral blood expression profiles correlate with biopsy-proven rejection, and that these changes could be used as biomarkers for the diagnosis and prediction of acute rejection. This SuperSeries is composed of the SubSeries listed below. We performed cross-sectional microarray analysis of 103 matched peripheral blood samples collected at a single time point, tim

ORGANISM(S): Homo sapiens

SUBMITTER:  

PROVIDER: S-DIXA-D-1016 | biostudies-other |

REPOSITORIES: biostudies-other