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Investigation of gene expression signature induced by Alk5TD (active type I TGF-beta receptor)

ABSTRACT: BT474 cells stably expressing Alk5TD or vector (BT474-Alk5TD and BT474-pBMN, respectively) were compared for gene expression. Genes that were differentially expressed between the two cell lines were collected as the signature induced by Alk5TD expression. Keywords: Comparison of two cell types (BT474-Alk5TD and BT474-pBMN). BT474-pBMN was used as the reference line. RNA samples extracted from the two cell lines (BT474-Alk5TD and BT474-pBMN) were differentially labeled (BT474-Alk5TD with Cy5 and BT474-pBMN with Cy3) and analyzed. The experiment was performed in triplicate with independent samples.

ORGANISM(S): Homo sapiens

SUBMITTER: Wang SE 

PROVIDER: S-ECPF-GEOD-11293 | biostudies-other | 2008 Sep

REPOSITORIES: biostudies-other

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