Browse
Submit Data
Databases
API
Help

Dataset Information

8 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Identification of new markers of cutaneous melanoma invasion

ABSTRACT: T1C3 is a clonal cell line from a human melanoma tumor, expressing PNA lectin, and characterized by a high capacity of dermal invasion. IC8 is a clonal cell line from a human melanoma tumor, negative for PNA lectin, and non-invasive. To identify new gene markers involved in the mechanisms of early invasion, oligonuclotide microarrays were used to assess transcriptional chnages between the two cell lines. Dye-swap hybridization were performed. Slides were scanned with a Genepix 4000 microarray scanner (Axon Instruments, Molecular devices, Sunnyvale, CA). For each hybridized spot, the Cy3 and Cy5 fluorescence values were obtained by using Genepix Pro 4.0 software (Axon Instruments) and were saved as a result file.

ORGANISM(S): Homo sapiens

SUBMITTER: Lamartine Jerome

PROVIDER: S-ECPF-GEOD-15802 | biostudies-other |

REPOSITORIES: biostudies-other

ACCESS DATA

Json Xml

Similar Datasets

Identification of new markers of cutaneous melanoma invasion

Project description:T1C3 is a clonal cell line from a human melanoma tumor, expressing PNA lectin, and characterized by a high capacity of dermal invasion. IC8 is a clonal cell line from a human melanoma tumor, negative for PNA lectin, and non-invasive. To identify new gene markers involved in the mechanisms of early invasion, oligonuclotide microarrays were used to assess transcriptional chnages between the two cell lines. Dye-swap hybridization were performed. Slides were scanned with a Genepix 4000 microarray scanner (Axon Instruments, Molecular devices, Sunnyvale, CA). For each hybridized spot, the Cy3 and Cy5 fluorescence values were obtained by using Genepix Pro 4.0 software (Axon Instruments) and were saved as a result file.

2010-12-15 | E-GEOD-15802 | biostudies-arrayexpress

Identification of new markers of cutaneous melanoma invasion

2010-12-15 | GSE15802 | GEO

Identification of Immune Function-Related Subtypes in Cutaneous Melanoma.

Project description: Not available

| S-EPMC8467264 | biostudies-literature

Identification of a Robust Methylation Classifier for Cutaneous Melanoma Diagnosis.

Project description: Not available

| S-EPMC6535139 | biostudies-literature

Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma.

Project description: Not available

| S-EPMC5458482 | biostudies-literature

Identification of New Diagnostic Protein Markers for Colorectal Cancer

Project description:The search for biochemical markers in patient’s blood for non-invasive colorectal cancer diagnostic has not yielded satisfactory results to date. The search for blood in the stool by enzymatic techniques has certainly allowed the diminution of colorectal cancer mortality but its low sensitivity is still a disadvantage. The new immunological tests for search blood test in the stool are more sensitive and more specific but still insufficient. The originality of this project is based on the use of new technology developed in fundamental research based on the detection of circulating exosomes from tumor cells in the patient’s serum. The detection of protein markers transported by tumor exosomes is original and innovative approach because it’s still not considered in the literature. The use of innovative and non-invasive health technologies for the patient is an important factor in the care of patients in their health care journey. The non-invasive nature of the project could reduce the reticence of patients to participate in cancer screening. The results expected from the study can have a direct impact on the management of patients suspected of having colon cancer and thus make it possible to optimize the earliness of their diagnosis.

| 2339705 | ecrin-mdr-crc

Objective assessment of blood and lymphatic vessel invasion and association with macrophage infiltration in cutaneous melanoma.

Project description: Not available

| S-EPMC3318158 | biostudies-other

Identification of subtypes correlated with tumor immunity and immunotherapy in cutaneous melanoma.

Project description: Not available

| S-EPMC8379294 | biostudies-literature

The Identification of Prognostic and Metastatic Alternative Splicing in Skin Cutaneous Melanoma.

Project description: Not available

| S-EPMC8743934 | biostudies-literature

Identification of Potential Prognostic Biomarkers Associated With Cancerometastasis in Skin Cutaneous Melanoma.

Project description: Not available