Transcription profiling by array of human neuroblastomas: MAQC-II project quality control phase II

ABSTRACT: "The MAQC-II Project: A comprehensive study of common practices for the development and validation of microarray-based predictive models The second phase of the MicroArray Quality Control (MAQC-II) project evaluated common practices for developing and validating microarray-based models aimed at predicting toxicological and clinical endpoints. The purposes of the MAQC-II project were to survey approaches in genomic model development in an attempt to understand sources of variability in prediction performance, and to assess the influences of endpoint signal strength in data. Thirty-six teams developed classifiers for 13 diverse endpoints -- some easy, some difficult to predict, from six relatively large training data sets -- three preclinical (toxicogenomics) and three clinical. By prov

ORGANISM(S): Homo sapiens

SUBMITTER: Shi Leming 

PROVIDER: S-ECPF-GEOD-16716 | biostudies-other |

REPOSITORIES: biostudies-other