Unique RNA Expression Patterns in Serum Exosomes from Patients with Glioblastoma Multiforme

ABSTRACT: Comparative expression analysis of RNA isolated from microvesicles from serum from glioblastoma multiforme (GBM) patients and normal healthy individuals. Blood samples from 9 patients diagnosed with de-novo primary GBM were collected immediately prior to surgery. Blood from 7 normal healthy controls was collected from volunteers recruited at the MGH blood bank. From each sample, RNA was isolated from microvesicles isolated from 1 mL of serum, and the RNA was linearly amplified and labeled with Cy3. The amplified and labeled RNA was hybridized to 16 individual Agilent Arrays.

ORGANISM(S): Homo sapiens

SUBMITTER: Noerholm Mikkel 

PROVIDER: S-ECPF-GEOD-24084 | biostudies-other |

REPOSITORIES: biostudies-other