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Expression data from melanoma cell lines

ABSTRACT: Differential gene expression analysis of parental and resistant sub-lines of melanoma cell lines treated or untreated with PLX4032 Using microarray we sought to obtain a genome-wide profile of differentially expressed genes in parental melanoma cell lines and resistant sub-lines in response to PLX4032 vs DMSO control treatment. Representative parental melanoma cell lines and resistant sub-lines were treated with PLX4032 at 1 uM or DMSO control for 6h. Total RNA was extracted and cDNAs were generated and hybridized onto GeneChip Human Gene 1.0 ST Arrays (Affymetrix).

ORGANISM(S): Homo sapiens

SUBMITTER: Nazarian R 

PROVIDER: S-ECPF-GEOD-24862 | biostudies-other | 2010 Dec

REPOSITORIES: biostudies-other

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2010-12-01 | GSE25436 | GEO