Expression Profiling of Pancreatic Xenografts and Cell Lines
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ABSTRACT: Expression profiling of 70 Pancreatic Ductal Adenocarcinoma (PDAC) samples was performed on Agilent 44K expression arrays for cancer gene discovery. Additionally, matched aCGH on Agilent 244K arrays was performed. These two datasets were integrated in order to identify driver mutations leading to pancreatic cancer. Promising candidates were interrogated further using functional studies. 68 tumor samples (48 xenografts, 20 cell lines). 2 color arrays hybridized against a common reference pool of RNA from 11 cancer cell lines
ORGANISM(S): Homo sapiens
SUBMITTER: Shain AH
PROVIDER: S-ECPF-GEOD-26088 | biostudies-other | 2012 Jan
REPOSITORIES: biostudies-other
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