Targeting of mitochondrial Hsp90 with Gamitrinib, G-TPP, in U251 glioblastoma cells

ABSTRACT: U251 gliolbastoma cells were treated with vehicle (DMSO) or G-TPP, a mitochondrial targeted version of 17-AAG. 6 hours after treatment RNA was harvested and subjected to microarray analysis on Human Gene 1.0 ST Array. We sought to determine a mitochdondrial gene response after targeting inhibition of mitochondrial chaperones, Hsp90.

ORGANISM(S): Homo sapiens

SUBMITTER: Siegelin Markus 

PROVIDER: S-ECPF-GEOD-26313 | biostudies-other |

REPOSITORIES: biostudies-other