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Promoter context-specific positive and negative transcriptional regulation of Glucocorticoid Receptor target genes by coregulator G9a

ABSTRACT: A549 lung cancer cells were not infected (NI), transfected by plasmids containing shG9a (sequence targeting G9a gene) or shNS (non-specific sequence). These cells were treated with dex to identify subsets of genes regulated by dex (hormone) and G9a (EHMT2) Cells (NI/shNS/shG9a) were treated with 100nM dex for 24h and total RNA was extracted to identify differentially expressed genes

ORGANISM(S): Homo sapiens

SUBMITTER: Wu Dai-Ying

PROVIDER: S-ECPF-GEOD-35962 | biostudies-other |

REPOSITORIES: biostudies-other

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