Gene expression analysis of recurrent metastatic melanoma lesions

ABSTRACT: In this study, we sought to indentify stable individual traits in developing metastatic melanoma, assess their stability in time, and analyze typical dynamics and common trends of genomic changes in individual cases of late stage metastatic cancer. To this end, we compared consecutive recurrent metastases developed by a special group of eight individuals with advanced metastatic melanoma, all developing several recurrent metastases over several months to years of natural disease evolution. Twenty-six recurrent melanoma metastases were surgically isolated from 8 patients experiencing relapse after one or more successful treatment intervention(s) with no signs of residual disease. Patients experiencing recurrent metastases were labeled with capital letters; “A”, “B”, “C”, etc., their subsequ

ORGANISM(S): Homo sapiens

SUBMITTER: Pos Zoltan 

PROVIDER: S-ECPF-GEOD-38119 | biostudies-other |

REPOSITORIES: biostudies-other