Project description:To improve our understanding of the relationships between methylation and expression we profiled mRNA expression and single-base resolution methylation levels for two breast cancer cell lines, MCF7 and T47D. Expression was profiled using RNA-seq. Methylation was assayed using Methyl-MAPS, which uses methylation-sensitive and -dependent restriction enzyme digests followed by high-throughput sequencing to identify methylation levels at individual CpGs (Edwards et al. 2010, Genome Research).

2013-06-15 | GSE45336 | GEO

Genome-wide methylation and expression analysis of two breast cancer cell lines [RNA-Seq]

2013-06-15 | GSE45335 | GEO

Genome-wide methylation and expression analysis of two breast cancer cell lines [RNA-Seq]

2013-06-15 | E-GEOD-45335 | biostudies-arrayexpress