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Effects of YB-1 protein reduction on microRNA abundance in breast cancer cell-lines


ABSTRACT: To assess the association of the nucleic acid binding protein yb-1 with mature microRNAs levels in breast cancer. To do this we performed YB-1 siRNA treatement in triplicates alongside an siRNA control Two breast cancer cell-lines, representative of Luminal A and Basal molecular subtypes were used, MCF7 and MDA-MB-435S. Two cell-lines, treated with either siYB-1 or si-Ctrl in triplicate samples.

ORGANISM(S): Homo sapiens

SUBMITTER: Blenkiron C 

PROVIDER: S-ECPF-GEOD-50087 | biostudies-other | 2013

REPOSITORIES: biostudies-other

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